Major cation in the intracellular fluid in animals is: 

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DSSSB PGT Chemistry (Female) Official Paper (Held On: 06 Jul, 2018 Shift 1)
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  1. Sodium
  2. Potassium 
  3. Calcium 
  4. Magnesium 

Answer (Detailed Solution Below)

Option 2 : Potassium 
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Detailed Solution

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CONCEPT:

Intracellular and extracellular cation distribution

  • Cations are positively charged ions that play a critical role in cellular functions, including nerve signaling, muscle contraction, and maintaining osmotic balance.
  • The major cation in intracellular fluid (fluid inside cells) is Potassium (K+), while the major cation in extracellular fluid (fluid outside cells) is Sodium (Na+).
  • This distribution is maintained by ion pumps like the sodium-potassium pump, which actively transports sodium out of the cell and potassium into the cell.

EXPLANATION:

  • In animals, the intracellular fluid (ICF) has a high concentration of potassium ions (K+) and a low concentration of sodium ions (Na+).
  • Potassium plays a crucial role in:
    • Maintaining the resting membrane potential of cells, especially in neurons and muscle cells.
    • Regulating cellular osmotic pressure and enzyme activity.
  • Other cations like sodium, calcium, and magnesium are present in much lower concentrations inside the cell compared to potassium.
  • Hence, the major cation in intracellular fluid is Potassium (K+).

Therefore, the correct answer is Potassium.

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