What is the expanded form of the term ‘mRNA’ that has been widely discussed since the beginning of the pandemic?

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69th BPSC Prelims Exam Official Paper (Held On: 30 Sept, 2023)
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  1. Messenger Ribonucleic Acid
  2. Mutant Ribonucleic Acid
  3. Modified Ribonucleic Acid
  4. Mnemonic Ribonucleic Acid

Answer (Detailed Solution Below)

Option 1 : Messenger Ribonucleic Acid
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Ancient History: Prehistoric Period
10 Qs. 10 Marks 8 Mins

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The correct answer is Messenger Ribonucleic Acid.

Key Points mRNA:

  • The term "mRNA" stands for "messenger RNA."
  • mRNA is a single-stranded molecule that is complementary to the DNA template strand from which it was transcribed.
  • The sequence of nucleotides in the mRNA carries the instructions for the specific sequence of amino acids in a protein.
  • Messenger RNA is a type of RNA (ribonucleic acid) molecule that plays a crucial role in the process of protein synthesis within cells.
  • During the COVID-19 pandemic, mRNA technology has gained significant attention due to the development of mRNA vaccines, such as the Pfizer-BioNTech and Moderna COVID-19 vaccines.
  • These vaccines use synthetic mRNA to instruct cells to produce a modified spike protein found on the surface of the SARS-CoV-2 virus, which triggers an immune response and helps protect against COVID-19.
  • The use of mRNA technology in vaccines has been a major breakthrough in the fight against the pandemic.
  • During the pandemic mRNA is detected by RT-PCR for diagnosis of disease. 

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