Which one among the following separation techniques is used for blood tests in diagnostic laboratories ? 

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NDA-II 2024 (GAT) Official Paper (Held On: 01 Sept, 2024)
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  1. Filtration 
  2. Chromatography  
  3. Centrifugation 
  4. Crystallization 

Answer (Detailed Solution Below)

Option 3 : Centrifugation 
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NDA 01/2025: English Subject Test
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Detailed Solution

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The correct answer is Centrifugation

Explanation:

  • Centrifugation is a technique that involves the use of centrifugal force to separate components of a mixture based on their density.
  • It is widely used in laboratories for the analysis of blood samples, among other applications.
  • In blood tests, centrifugation helps to separate blood cells from plasma or serum, which is essential for various diagnostic tests.
  • The rate of separation in a suspension of particles by way of gravitational force mainly depends on the particle size and density.
  • Particles of higher density or larger size typically travel at a faster rate and at some point will be separated from particles less dense or smaller.
  • In blood tests, centrifugation is employed to separate the different components of blood, such as plasma, red blood cells (erythrocytes), white blood cells (leukocytes), and platelets.

Other Options:

  • Filtration: This technique is used to separate solids from liquids or gases using a filter medium that allows only the fluid to pass through. It is not suitable for separating components of blood.
  • Chromatography: This method is used to separate and analyze components of a mixture based on their movement through a stationary phase. While useful for many applications, it is not typically used for routine blood tests in diagnostic laboratories.
  • Crystallization: This process involves the formation of solid crystals from a homogeneous solution. It is generally used in chemical processes for purifying substances and not for blood analysis.
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