The causal organism of dengue fever is a mosquito-borne virus which belongs to which one among the following categories? 

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CDS General Knowledge 21 April 2024 Official Paper
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  1. Flavi-ribo virus
  2. Adenovirus
  3. Vaccinia virus
  4. Nipah virus

Answer (Detailed Solution Below)

Option 1 : Flavi-ribo virus
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The correct answer is Flavi-ribo virus.

Key Points

  • Dengue fever is caused by a virus belonging to the Flavivirus genus, which is part of the larger Flaviviridae family that includes several other significant viruses.
  • This virus is transmitted to humans through the bites of infected Aedes mosquitoes, primarily Aedes aegypti, but also Aedes albopictus.
  • The Flavivirus genus also includes other notable pathogens such as the West Nile virus, Yellow fever virus, and the Zika virus, all of which are transmitted by mosquitoes.
  • The term “flavi” in Latin means “yellow,” reflecting the Yellow fever virus's jaundice symptom, another disease caused by a flavivirus.
  • Dengue virus has four distinct serotypes (DENV-1, DENV-2, DENV-3, and DENV-4), and infection with one serotype provides lifelong immunity against that specific serotype but not the others.
  • Infection can lead to a range of conditions from mild fever to severe forms like dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS).

 Additional Information

  • Adenovirus: A type of DNA virus that causes a range of illnesses, from mild respiratory infections to gastroenteritis.
  • Vaccinia virus: Used in the smallpox vaccine, this virus is a member of the poxvirus family and is not naturally occurring in humans but developed for vaccination purposes.
  • Nipah virus: A zoonotic virus transmitted from animals to humans, connected to severe diseases in both animals and humans, notably respiratory and neurological diseases. It has been identified as a prioritized virus by the WHO due to its potential to cause epidemics.
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